Tribulus

October 2, 2020

Overview

Tribulus is a plant that produces fruit covered with spines. Rumor has it that tribulus is also known as puncture vine because its sharp spines can flatten bicycle tires. People use the fruit, leaf, and root as medicine.

People use tribulus for conditions such as chest pain, eczema, enlarged prostate, sexual disorders, infertility, and many others, but there is no good scientific evidence to support these uses.

Classification

Is a Form of:

Plant

Primary Functions:

Chest Pain, eczema, enlarged prostate

Also Known As:

Baijili, Bindii, Bulgarian Tribulus Terrestris, Caltrop

How Does It Work?

Tribulus has chemicals that might increase levels of some hormones. However, it doesn't appear to increase male hormones (testosterone) in humans.

Uses

Sexual problems that prevent satisfaction during sexual activity.Research shows that taking tribulus can improve the sexual experience in women who have sexual dysfunction or low sexual desire. Taking tribulus seems to improve sexual desire, arousal, sensation, ability to reach orgasm, lubrication, and sexual comfort. Early research also shows that taking tribulus can improve sexual satisfaction in men with erectile dysfunction.

Recommended Dosing

The following doses have been studied in scientific research:

ADULTS

BY MOUTH:

For sexual problems that prevent satisfaction during sexual activity: 250 mg tribulus powdered extract three times daily taken after meals for 3 months has been used for women. Also, tribulus extract 7.5 mg daily for 4 weeks has been used for women. 500 mg three times daily for 3 months has been used for men.

Tribulus Supplements Frequently Asked Questions

What are the health benefits of Tribulus?

Tribulus is used for kidney problems, including kidney stones, painful urination, a kidney disorder called Bright's disease, and as a “water pill” (diuretic) to increase urination; for skin disorders, including eczema (atopic dermatitis), psoriasis, and scabies; for male sexual problems, including erectile dysfunction

Can I take Tribulus everyday?

Tribulus is very dose-specific, so you need to get the timing and amount correct before seeing the results you want. The range that appears to work for most people is between 2.3 and 4.6 milligrams of protodioscin per pound of body weight every day.

What are the side effects of Tribulus?

Side effects are usually mild and uncommon but might include stomach pain, cramping, diarrhea, nausea, vomiting, constipation, excitation, difficulty sleeping, or heavy menstrual bleeding. In rare cases, reports of kidney damage have been linked to taking tribulus.

Is Tribulus a steroid?

[Steroid saponins of Tribulus terrestris L. have a stimulant effect on the sexual function].

Does Tribulus help erectile dysfunction?

Summary: Research has found that Tribulus terrestris may improve libido in women and men with reduced sex drives. Studies on the herb as a treatment for erectile dysfunction have shown mixed results, with higher doses appearing to be more beneficial.

What are 5 foods that boost testosterone?

How this works.

Eating for higher T. Testosterone is a male sex hormone that affects more than just sex drive.
Tuna is rich in vitamin D, which has been linked to a longer life and testosterone production.
Low-fat milk with vitamin D.
Egg yolks.
Fortified cereals.

How long should I take Tribulus terrestris?

BY MOUTH: For sexual problems that prevent satisfaction during sexual activity: 250 mg tribulus powdered extract three times daily taken after meals for 3 months has been used for women. Also, tribulus extract 7.5 mg daily for 4 weeks has been used for women. 500 mg three times daily for 3 months has been used for men.

Is Tribulus worth taking?

And although it doesn't increase testosterone, Tribulus terrestris may improve libido in men and women. However, it won't improve body composition or exercise performance. While most research shows that this supplement is safe and causes only minor side effects, there have been isolated reports of toxicity.

Is Tribulus good for kidneys?

Conclusions: Oral administration of Tribulus terrestris extract for 2 weeks can decrease kidney functional disturbance, oxidative stress, and cellular damages following reperfusion injury in rats.

Does testosterone increase size?

Testosterone is responsible for increased muscle mass. Leaner body mass helps control weight and increases energy. For men with low testosterone, studies show that treatment can decrease fat mass and increase muscle size and strength. Some men reported a change in lean body mass but no increase in strength.

Does Tribulus raise testosterone?

In humans, there is some evidence that it may improve blood sugar control and cholesterol levels in people with type 2 diabetes. And although it doesn't increase testosterone, Tribulus terrestris may improve libido in men and women. However, it won't improve body composition or exercise performance.

Does Tribulus increase DHT?

Abstract. Hormonal effects of Tribulus terrestris (TT) were evaluated in primates, rabbit and rat to identify its usefulness in the management of erectile dysfunction (ED). In primates, the increases in T (52%), DHT (31%) and DHEAS (29%) at 7.5mg/kg were statistically significant.

Does Tribulus affect sperm count?

Try tribulusterrestris. Tribulusterrestris, also known as puncture vine, is a medicinal herb frequently used to enhance male fertility. One study in men with low sperm counts showed that taking 6 grams of tribulus root twice daily for 2 months improved erectile function and libido ( 31 ).

Does Tribulus raise estrogen?

In animal studies, Tribulus increased sex hormones (e.g., testosterone) and improved nitric oxide synthesis; however, these results have not been observed in some human studies. Explanation: differences in extract and plant parts and the fact that studies included healthy males with normal testosterone.

Where does Tribulus terrestris grow?

Tribulus terrestris is an annual plant in the caltrop family (Zygophyllaceae) widely distributed around the world. It is adapted to grow in dry climate locations in which few other plants can survive. It is native to warm temperate and tropical regions in southern Eurasia, Africa, North America, and Australia.

When should I take Tribulus terrestris bodybuilding?

I recommend taking Tribulus on an empty stomach with water only or a zero- or very-low-calorie drink. On training days, consume one dose when you wake up in the morning, and another prior to training. On non-training days, consume the second dose mid-day.

How much Tribulus should a woman take?

For sexual problems that prevent satisfaction during sexual activity: 250 mg tribulus powdered extract three times daily taken after meals for 3 months has been used for women. Also, tribulus extract 7.5 mg daily for 4 weeks has been used for women. 500 mg three times daily for 3 months has been used for men.

What part of Tribulus terrestris is used?

Tribulus terrestris is a fruit-producing Mediterranean plant that's covered with spines. It is also called puncture vine. People use the fruit, leaf, or root of the tribulus plant as medicine.

Does Tribulus build muscle?

Tribulus terrestris is an herbal nutritional supplement that is promoted to produce large gains in strength and lean muscle mass in 5-28 days (15, 18). terrestris may increase the urinary testosterone/epitestosterone (T/E) ratio, which may place athletes at risk of a positive drug test.

What is Bulgarian Tribulus?

Bulgarian Tribulus is a natural supplement derived from the Tribulus terrestris. It helps boost testosterone, support greater muscle growth, and increase strength and stamina.

Is Tribulus terrestris safe?

Clinical Studies

^ a b c Comparison of Murraya koenigii- and Tribulus terrestris-based oral formulation versus tamsulosin in the treatment of benign prostatic hyperplasia in men aged >50 years: a double-blind, double-dummy, randomized controlled trial.
^ a b Iacono F, et al. Observational study: daily treatment with a new compound "Tradamixina" plus serenoa repens for two months improved the lower urinary tract symptoms. BMC Surg. (2012)
^ a b Iacono F, et al. Sexual asthenia: Tradamixina versus Tadalafil 5 mg daily. BMC Surg. (2012)
^ a b Sharma J, et al. The treatment of jaundice with medicinal plants in indigenous communities of the Sub-Himalayan region of Uttarakhand, India. J Ethnopharmacol. (2012)
^ a b Xu YJ, et al. Two new furostanol saponins from Tribulus terrestris. J Asian Nat Prod Res. (2010)
^ A comparative phylogenetic analysis of medicinal plant Tribulus terrestris in Northwest India revealed by RAPD and ISSR markers.
^ Mutheeswaran S, et al. Documentation and quantitative analysis of the local knowledge on medicinal plants among traditional Siddha healers in Virudhunagar district of Tamil Nadu, India. J Ethnopharmacol. (2011)
^ a b Deole YS, et al. Evaluation of anti-depressant and anxiolytic activity of Rasayana Ghana Tablet (A compound Ayurvedic formulation) in albino mice. Ayu. (2011)
^ a b Kevalia J, Patel B. Identification of fruits of Tribulus terrestris Linn. and Pedalium murex Linn.: A pharmacognostical approach. Ayu. (2011)
^ a b Olas B, et al. Evaluation of polyphenolic fraction isolated from aerial parts of Tribulus pterocarpus on biological properties of blood platelets in vitro. Platelets. (2012)
^ Flavonoid glycosides of Tribulus pentandrus and T. Terrestris.
^ Temraz A, et al. Steroidal saponins from the aerial parts of Tribulus alatus Del. Phytochemistry. (2006)
^ a b El-Tantawy WH, Temraz A, El-Gindi OD. Free serum testosterone level in male rats treated with Tribulus alatus extracts. Int Braz J Urol. (2007)
^ a b c d e f g h i Dinchev D, et al. Distribution of steroidal saponins in Tribulus terrestris from different geographical regions. Phytochemistry. (2008)
^ AN IMPROVED METHOD FOR THE EXTRACTION AND QUANTITATION OF DIOSGENIN IN TRIBULUS TERRESTRIS L.
^ a b c Zhang S, Li H, Yang SJ. Tribulosin suppresses apoptosis via PKC epsilon and ERK1/2 signaling pathway during hypoxia/reoxygenation in neonatal rat ventricular cardiac myocytes. J Asian Nat Prod Res. (2011)
^ a b Sun W, Li H, Yang SJ. A triterpene saponin from Tribulus terrestris attenuates apoptosis in cardiocyte via activating PKC signalling transduction pathway. J Asian Nat Prod Res. (2008)
^ a b Conrad J, et al. A novel furostanol saponin from Tribulus terrestris of Bulgarian origin. Fitoterapia. (2004)
^ Su L, et al. Steroidal saponins from Tribulus terrestris. Steroids. (2009)
^ Hammoda HM, et al. Chemical constituents from Tribulus terrestris and screening of their antioxidant activity. Phytochemistry. (2013)
^ a b c Aggarwal A, et al. A novel antilithiatic protein from Tribulus terrestris having cytoprotective potency. Protein Pept Lett. (2012)
^ a b c d Gacche RN, Dhole NA. Profile of aldose reductase inhibition, anti-cataract and free radical scavenging activity of selected medicinal plants: an attempt to standardize the botanicals for amelioration of diabetes complications. Food Chem Toxicol. (2011)
^ Chen G, et al. New steroidal glycosides from Tribulus terrestris L. J Asian Nat Prod Res. (2012)
^ Coates TJ, Lo B. Counseling patients seropositive for human immunodeficiency virus. An approach for medical practice. West J Med. (1990)
^ Wang J, Zu X, Jiang Y. Five furostanol saponins from fruits of Tribulus terrestris and their cytotoxic activities. Nat Prod Res. (2009)
^ Xu T, et al. Two new furostanol saponins from Tribulus terrestris L. Fitoterapia. (2009)
^ Liu T, et al. Two new steroidal saponins from Tribulus terrestris L. J Asian Nat Prod Res. (2010)
^ a b Liu T, et al. New pregnane and steroidal glycosides from Tribulus terrestris L. J Asian Nat Prod Res. (2010)
^ a b Li JX, et al. Tribulusamide A and B, new hepatoprotective lignanamides from the fruits of Tribulus terrestris: indications of cytoprotective activity in murine hepatocyte culture. Planta Med. (1998)
^ a b c Byun E, et al. Tribuli fructus constituents protect against tacrine-induced cytotoxicity in HepG2 cells. Arch Pharm Res. (2010)
^ Zhang X, et al. A new feruloyl amide derivative from the fruits of Tribulus terrestris. Nat Prod Res. (2012)
^ Kostova I, et al. Two new sulfated furostanol saponins from Tribulus terrestris. Z Naturforsch C. (2002)
^ a b Jarald EE, et al. Effect of Unex on ethylene glycol-induced urolithiasis in rats. Indian J Pharmacol. (2011)
^ a b c d e f g h Gandhi S, Srinivasan BP, Akarte AS. Potential nephrotoxic effects produced by steroidal saponins from hydro alcoholic extract of Tribulus terrestris in STZ-induced diabetic rats. Toxicol Mech Methods. (2013)
^ Orhan I, et al. Acetylcholinesterase and butyrylcholinesterase inhibitory activity of some Turkish medicinal plants. J Ethnopharmacol. (2004)
^ a b c d Gauthaman K, Ganesan AP, Prasad RN. Sexual effects of puncturevine (Tribulus terrestris) extract (protodioscin): an evaluation using a rat model. J Altern Complement Med. (2003)
^ a b c Wang Z, et al. Effect of tribulus terrestris saponins on behavior and neuroendocrine in chronic mild stress depression rats. J Tradit Chin Med. (2013)
^ a b Heidari MR, et al. The analgesic effect of Tribulus terrestris extract and comparison of gastric ulcerogenicity of the extract with indomethacine in animal experiments. Ann N Y Acad Sci. (2007)
^ Ranjithkumar R, et al. Standardized Aqueous Tribulus terristris (Nerunjil) Extract Attenuates Hyperalgesia in Experimentally Induced Diabetic Neuropathic Pain Model: Role of Oxidative Stress and Inflammatory Mediators. Phytother Res. (2012)
^ Mazaro-Costa R, et al. Medicinal plants as alternative treatments for female sexual dysfunction: utopian vision or possible treatment in climacteric women. J Sex Med. (2010)
^ Wang SS, et al. Mechanisms of gross saponins of Tribulus terrestris via activating PKCepsilon against myocardial apoptosis induced by oxidative stress. Yao Xue Xue Bao. (2009)
^ a b Zhang S, Li H, Yang SJ. Tribulosin protects rat hearts from ischemia/reperfusion injury. Acta Pharmacol Sin. (2010)
^ Dong S, et al. Post-conditioning protects cardiomyocytes from apoptosis via PKC(epsilon)-interacting with calcium-sensing receptors to inhibit endo(sarco)plasmic reticulum-mitochondria crosstalk. Mol Cell Biochem. (2010)
^ Zhang J, et al. ERK-MAPK signaling opposes rho-kinase to reduce cardiomyocyte apoptosis in heart ischemic preconditioning. Mol Med. (2010)
^ a b c d e f Murthy AR, Dubey SD, Tripathi K. Anti-hypertensive effect of Gokshura (Tribulus terrestris Linn.) - A clinical study. Anc Sci Life. (2000)
^ Somanadhan B, et al. An ethnopharmacological survey for potential angiotensin converting enzyme inhibitors from Indian medicinal plants. J Ethnopharmacol. (1999)
^ Sharifi AM, Darabi R, Akbarloo N. Study of antihypertensive mechanism of Tribulus terrestris in 2K1C hypertensive rats: role of tissue ACE activity. Life Sci. (2003)
^ Sajid TM, Rashid S, Saeed SA. Inhibition of adrenaline-induced aggregation of human platelets by Pakistani medicinal plants. Pak J Pharm Sci. (1991)
^ Ponnusamy S, et al. Evaluation of traditional Indian antidiabetic medicinal plants for human pancreatic amylase inhibitory effect in vitro. Evid Based Complement Alternat Med. (2011)
^ a b c Zhang SJ, Qu WJ, Zhong SY. Inhibitory effects of saponins from Tribulus terrestris on alpha-glucosidase in small intestines of rats. Zhongguo Zhong Yao Za Zhi. (2006)
^ a b Amin A, et al. The protective effect of Tribulus terrestris in diabetes. Ann N Y Acad Sci. (2006)
^ Antonio J, et al. The effects of Tribulus terrestris on body composition and exercise performance in resistance-trained males. Int J Sport Nutr Exerc Metab. (2000)
^ a b Rogerson S, et al. The effect of five weeks of Tribulus terrestris supplementation on muscle strength and body composition during preseason training in elite rugby league players. J Strength Cond Res. (2007)
^ Hong CH, et al. Evaluation of natural products on inhibition of inducible cyclooxygenase (COX-2) and nitric oxide synthase (iNOS) in cultured mouse macrophage cells. J Ethnopharmacol. (2002)
^ a b Gauthaman K, Adaikan PG. Effect of Tribulus terrestris on nicotinamide adenine dinucleotide phosphate-diaphorase activity and androgen receptors in rat brain. J Ethnopharmacol. (2005)
^ Vincent SR, Kimura H. Histochemical mapping of nitric oxide synthase in the rat brain. Neuroscience. (1992)
^ a b Martino-Andrade AJ, et al. Effects of Tribulus terrestris on endocrine sensitive organs in male and female Wistar rats. J Ethnopharmacol. (2010)
^ Nahata A, Dixit VK. Evaluation of 5α-reductase inhibitory activity of certain herbs useful as antiandrogens. Andrologia. (2013)
^ a b Gauthaman K, Ganesan AP. The hormonal effects of Tribulus terrestris and its role in the management of male erectile dysfunction--an evaluation using primates, rabbit and rat. Phytomedicine. (2008)
^ a b c d e Singh S, Nair V, Gupta YK. Evaluation of the aphrodisiac activity of Tribulus terrestris Linn. in sexually sluggish male albino rats. J Pharmacol Pharmacother. (2012)
^ a b c d Aphrodisiac activity of Tribulus terrestris Linn. in experimental models in rats.
^ Neychev VK, Mitev VI. The aphrodisiac herb Tribulus terrestris does not influence the androgen production in young men. J Ethnopharmacol. (2005)
^ Saudan C, et al. Short term impact of Tribulus terrestris intake on doping control analysis of endogenous steroids. Forensic Sci Int. (2008)
^ Guidance for Industry Estimating the Maximum Safe Starting Dose in Initial Clinical Trials for Therapeutics in Adult Healthy Volunteers.
^ Brown GA, et al. Effects of anabolic precursors on serum testosterone concentrations and adaptations to resistance training in young men. Int J Sport Nutr Exerc Metab. (2000)
^ Brown GA, et al. Effects of androstenedione-herbal supplementation on serum sex hormone concentrations in 30- to 59-year-old men. Int J Vitam Nutr Res. (2001)
^ Brown GA, et al. Endocrine and lipid responses to chronic androstenediol-herbal supplementation in 30 to 58 year old men. J Am Coll Nutr. (2001)
^ a b c d Sellandi TM, Thakar AB, Baghel MS. Clinical study of Tribulus terrestris Linn. in Oligozoospermia: A double blind study. Ayu. (2012)
^ Dimitrov M, Georgiev P, Vitanov S. Use of tribestan on rams with sexual disorders. Vet Med Nauki. (1987)
^ a b Lakshmi GD, et al. Protective effect of Tribulus terrestris linn on liver and kidney in cadmium intoxicated rats. Indian J Exp Biol. (2012)
^ a b Jagadeesan G, Kavitha AV. Recovery of phosphatase and transaminase activity of mercury intoxicated Mus musculus (Linn.) liver tissue by Tribulus terrestris (Linn.) (Zygophyllaceae) extract. Trop Biomed. (2006)
^ a b Jagadeesan G, Kavitha AV, Subashini J. FT-IR Study of the influence of Tribulus terrestris on Mercury intoxicated mice, Mus musculus liver. Trop Biomed. (2005)
^ Kim HJ, et al. Aqueous extract of Tribulus terrestris Linn induces cell growth arrest and apoptosis by down-regulating NF-κB signaling in liver cancer cells. J Ethnopharmacol. (2011)
^ Kavitha AV, Jagadeesan G. Role of Tribulus terrestris (Linn.) (Zygophyllacea) against mercuric chloride induced nephrotoxicity in mice, Mus musculus (Linn.). J Environ Biol. (2006)
^ a b Talasaz AH, et al. Tribulus terrestris-induced severe nephrotoxicity in a young healthy male. Nephrol Dial Transplant. (2010)
^ a b Schmidt M, Thomsen M, Bone K. Tribulus terrestis-induced nephrotoxicity. Nephrol Dial Transplant. (2011)
^ a b Aggarwal A, et al. Diminution of oxalate induced renal tubular epithelial cell injury and inhibition of calcium oxalate crystallization in vitro by aqueous extract of Tribulus terrestris. Int Braz J Urol. (2010)
^ Shirfule AL, Sangamwar AT, Khobragade CN. Exploring glycolate oxidase (GOX) as an antiurolithic drug target: molecular modeling and in vitro inhibitor study. Int J Biol Macromol. (2011)
^ Anand R, et al. Activity of certain fractions of Tribulus terrestris fruits against experimentally induced urolithiasis in rats. Indian J Exp Biol. (1994)
^ Rajendar B, et al. Protective effect of an aphrodisiac herb Tribulus terrestris Linn on cadmium-induced testicular damage. Indian J Pharmacol. (2011)
^ a b Frydrychová S, et al. Effects of herbal preparation on libido and semen quality in boars. Reprod Domest Anim. (2011)
^ Kaplan SA. Re: Comparison of Murraya koenigii- and Tribulus terrestris-Based Oral Formulation Versus Tamsulosin in the Treatment of Benign Prostatic Hyperplasia in Men Aged >50 Years: A Double-Blind, Double-Dummy, Randomized Controlled Trial. J Urol. (2012)
^ Al-Ali M, et al. Tribulus terrestris: preliminary study of its diuretic and contractile effects and comparison with Zea mays. J Ethnopharmacol. (2003)
^ Gauthaman K, Adaikan PG, Prasad RN. Aphrodisiac properties of Tribulus Terrestris extract (Protodioscin) in normal and castrated rats. Life Sci. (2002)
^ a b c Do J, et al. Effects and Mechanism of Action of a Tribulus terrestris Extract on Penile Erection. Korean J Urol. (2013)
^ Kam SC, et al. In Vivo and in Vitro Animal Investigation of the Effect of a Mixture of Herbal Extracts from Tribulus terrestris and Cornus officinalis on Penile Erection. J Sex Med. (2012)
^ a b Adaikan PG, et al. Proerectile pharmacological effects of Tribulus terrestris extract on the rabbit corpus cavernosum. Ann Acad Med Singapore. (2000)
^ Yang L, et al. Effect of Tribulus terrestris extract on melanocyte-stimulating hormone expression in mouse hair follicles. Nan Fang Yi Ke Da Xue Xue Bao. (2006)
^ Deng Y, Yang L, An SL. Effect of Tribulus terrestris L decoction of different concentrations on tyrosinase activity and the proliferation of melanocytes. Di Yi Jun Yi Da Xue Xue Bao. (2002)
^ a b Sisto M, et al. Saponins from Tribulus terrestris L. protect human keratinocytes from UVB-induced damage. J Photochem Photobiol B. (2012)
^ Sancar A, et al. Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints. Annu Rev Biochem. (2004)
^ Arcasoy HB, et al. Effect of Tribulus terrestris L. saponin mixture on some smooth muscle preparations: a preliminary study. Boll Chim Farm. (1998)
^ a b Jameel JK, et al. Gynaecomastia and the plant product "Tribulis terrestris". Breast. (2004)
^ Aslani MR, et al. Experimental Tribulus terrestris poisoning in sheep: clinical, laboratory and pathological findings. Vet Res Commun. (2003)
^ Bourke CA. Hepatopathy in sheep associated with Tribulus terrestris. Aust Vet J. (1983)
de Souza KZ, Vale FB, Geber S. Efficacy of Tribulus terrestris for the treatment of hypoactive sexual desire disorder in postmenopausal women: a randomized, double-blinded, placebo-controlled trial. Menopause. (2016)
Roaiah MF, et al. Prospective Analysis on the Effect of Botanical Medicine (Tribulus terrestris) on Serum Testosterone Level and Semen Parameters in Males with Unexplained Infertility. J Diet Suppl. (2016)
Samani NB, et al. Efficacy of Tribulus Terrestris Extract on the Serum Glucose and Lipids of Women with Diabetes Mellitus. Iran J Med Sci. (2016)
GamalEl Din SF, et al. Tribulus terrestris versus placebo in the treatment of erectile dysfunction and lower urinary tract symptoms in patients with late-onset hypogonadism: A placebo-controlled study. Urologia. (2018)
Roaiah MF, et al. Pilot Study on the Effect of Botanical Medicine (Tribulus terrestris) on Serum Testosterone Level and Erectile Function in Aging Males With Partial Androgen Deficiency (PADAM). J Sex Marital Ther. (2016)
Gama CR, et al. Clinical Assessment of Tribulus terrestris Extract in the Treatment of Female Sexual Dysfunction. Clin Med Insights Womens Health. (2014)
Kamenov Z, et al. Evaluation of the efficacy and safety of Tribulus terrestris in male sexual dysfunction-A prospective, randomized, double-blind, placebo-controlled clinical trial. Maturitas. (2017)
Akhtari E, et al. Tribulus terrestris for treatment of sexual dysfunction in women: randomized double-blind placebo - controlled study. Daru. (2014)
Vale FBC, et al. Efficacy of Tribulus Terrestris for the treatment of premenopausal women with hypoactive sexual desire disorder: a randomized double-blinded, placebo-controlled trial. Gynecol Endocrinol. (2018)
Salgado RM, et al. Effect of oral administration of Tribulus terrestris extract on semen quality and body fat index of infertile men. Andrologia. (2017)