Overview

Inosine is a chemical that can be made in a laboratory. It is used as medicine.

People take inosine for improving their athletic performance. It is also used for multiple sclerosis (MS) and Parkinson's disease.

Classification

Is a Form of:

Chemical

Primary Functions:

Improving athletic performance

Also Known As:

Hypoxanthine Riboside, Hypoxanthosine, Inosina, 2,3-Diphosphoglycerate

How Does It Work?

When people take inosine by mouth it is changed in the body to make a chemical called uric acid. Uric acid acts like an antioxidant and might protect cells in the brain.

Uses

• Improving athletic performance. Early research shows that taking inosine does not help people to run faster or cycle farther.
• Multiple sclerosis (MS). Some research shows that having low uric acid levels increases the risk of developing MS. Research in adults with MS shows that taking inosine increases the levels of uric acid in the blood. However, it is not clear if this improves the symptoms of MS. More research in larger groups is needed to understand if increased uric acid levels helps to treat MS.

Recommended Dosing

The appropriate dose of inosine depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for inosine. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

Inosine Supplements Frequently Asked Questions

What foods contain inosine?

Animal and fish meats contain high amounts of inosine and its related purines, and the reduction of taking those purines is crucial for the improvement of serum uric acid levels.

What is inosine used for?

Inosine is a chemical that can be made in a laboratory. It is used as medicine. People take inosine for improving their athletic performance. It is also used for multiple sclerosis (MS) and Parkinson's disease.

What can inosine bind to?

Reactions. Adenine is converted to adenosine or inosine monophosphate (IMP), either of which, in turn, is converted into inosine (I), which pairs with adenine (A), cytosine (C), and uracil (U). Purine nucleoside phosphorylase intraconverts inosine and hypoxanthine.

Is inosine a purine or pyrimidine?

A nucleoside consists of a purine or pyrimidine base is linked to a pentose, either d-ribose to form a ribonucleoside or 2-deoxy-d-ribose to form a deoxyribonucleoside. Three major purine bases and their corresponding ribonucleosides are adenine/adenosine, guanine/guanosine, and hypoxanthine/ inosine.

Why is inosine important in tRNA function?

According to Crick's wobble hypothesis(2), inosine at position 34 is believed to play a crucial role in protein synthesis by allowing alternative pairing with U, C, or A in the third position of appropriate codons in the mRNA.

Clinical Studies