1,4-DMAA

Overview

1,4-DMAA is a chemical with stimulant effects.

1,4-DMAA is used for athletic performance and obesity, but there is no good scientific evidence to support these uses. Taking 1,4-DMAA might also be unsafe.

1,4-DMAA is found in small amounts in geranium plants. However, some supplements have been found to contain much larger amounts than are found in nature. Because of this, there is a concern that manufacturers are using synthetic 1,4-DMAA that is made in a laboratory rather than obtaining it from a natural source. The US Food and Drug Administration (FDA) states that supplements containing 1,4-DMAA appear to be illegal and recommends that these products not be taken. 1,4-DMAA is also included in the World Anti-Doping Agency's prohibited substances list. Competitive athletes should avoid taking it.

Classification

Is a Form of:

Chemical with stimulant effects

Primary Functions:

Athletic performance and obesity

Also  Known As:

1,4-Dimethylamylamine, 1,4-Dimethylpentylamine, 1,4 Dimethylamylamine, 1,4 Dimethylpentylamine, 1,4 DMAA

How Does It Work?

1,4-DMAA is thought to have stimulant effects. Stimulants can increase energy and focus and decrease hunger. However, there is no good scientific evidence to support the use of 1,4-DMAA for these effects.

Uses

  • Athletic performance.
  • Obesity.
  • Other conditions.

Recommended Dosing

The appropriate dose of 1,4-DMAA depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for 1,4-DMAA. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

1,4-DMAA Supplements Frequently Asked Questions

What does DMAA do to your body?

DMAA works by stimulating the neurotransmitter norepinephrine (noradrenaline). This increases heart rate, breathing rate, causes vasoconstriction, and can give the user feelings of intense focus, increased energy, alertness, and strength.

Is DMAA illegal?

DMAA is not a dietary ingredient, and DMAA-containing products marketed as dietary supplements are illegal and their marketing violates the law. The FDA continues to advise consumers not to buy or use products marketed as dietary supplements that contain DMAA due to the health risks they present.

Is DMAA a steroid?

DMAA is banned by the US Military because two soliders died after taking it during basic training. It's apparently serious stuff. It also has pregnenolone, a steroid hormone banned by the olympics so I figured that would give me some sort of insight into what taking an illegal steroid would be like.

Is DMAA banned in Australia?

The TGA has banned the use of the chemical 1,3-dimethylamylamine (DMAA). As of 8 August 2012 the use of DMAA is illegal. The TGA urges people not to obtain, supply or use DMAA. DMAA is a toxic substance with dangerous side effects.

Is DMAA like Adderall?

It's helps you really get pumped up.” Another main ingredient in these supplements is caffeine. However, the most controversial ingredient in some is 1-3 dimethylamylamine or DMAA. “1-3 dimethylamylamine is essentially like Adderall or Ritalin in a legalized form,” Balgobin said.

Why is DMAA bad?

Taking DMAA can raise blood pressure and lead to cardiovascular problems ranging from shortness of breath and tightening in the chest to heart attack. The FDA continues to advise consumers not to buy or use products marketed as dietary supplements that contain DMAA due to the health risks they present.

Does DMAA get you high?

DMAA or 1, 3-Dimethylamylamine is a very potent stimulant that has gained much popularity in sports performance drinks in recent years. Many companies marketing products containing DMAA claim that it is a “natural stimulant” derived from the seed, stem, or oil of the geranium plant.

Does DMAA lower testosterone?

DMAA at low concentrations decreased the ratio of 5 alpha-dihydrotestosterone to testosterone in the nuclei without significantly reducing the total uptake. This nuclear uptake of 5 alpha-dihydrotestosterone is inhibited only by high concentrations of DMAA.

Will DMAA fail a drug test?

Another drug that has been associated with false positive results for amphetamine is 1,3 dimethylamylamine (DMAA). DMAA has sympathomimetic activity and is an ingredient in some dietary and weight-loss supplements.

What does DMAA feel like?

DMAA works by stimulating the neurotransmitter norepinephrine (noradrenaline). This increases heart rate, breathing rate, causes vasoconstriction, and can give the user feelings of intense focus, increased energy, alertness, and strength.

Is DMAA safe?

The FDA does not have any information to demonstrate that consuming DMAA is safe. When DMAA is added to a product marketed as a dietary supplement, the FDA considers it to be an unsafe food additive. The FDA is very concerned about DMAA, and we advise consumers not to purchase or use any product containing DMAA.

Does DMAA test positive?

Service Members who ingest products containing DMAA may screen presumptively positive on the initial immunoassay tests for amphetamines. In the confirmation test by the GC-MS, DMAA does not cause a positive result for methamphetamine/amphetamine.

Is DMAA like speed?

DMAA is an aliphatic amine which looks a bit like amphetamine. Although it is a stimulant, it is not clear if DMAA actually works like amphetamine. DMAA is banned by most sporting bodies for use by athletes, but that is because it is a stimulant, and stimulants in general are banned by sporting bodies.

Is Dmha better than DMAA?

DMAA is delicately stronger. 70 mg of DMAA acts similary as 200 mg of DMHA. At the same time it's harder to get high quality supplements containing DMAA . That is why supplements containing DMAA are more expensive, than those with DMHA.

How long does it take for DMAA to kick in?

The peak DMAA concentration for all subjects was observed within 3–5 hours following ingestion and was very similar across subjects, with a mean of ~70 ng∙mL-1. Heart rate, blood pressure, and body temperature were largely unaffected by DMAA treatment.

Is DMAA natural?

Also known as methylhexanamine or geranium extract, DMAA is often touted as a “natural” stimulant; however, the FDA is not aware of any reliable science indicating that DMAA exists naturally in plants. DMAA, especially in combination with other stimulant ingredients such as caffeine, can be a health risk to consumers.

How much DMAA should I take?

The pills con- tained DMAA at an estimated dose of approximately 150 mg based on labeled dose information (lab analysis confirmed dosage of 132 mg), a dose approximately 3-5 times that normally suggested by most pre-workout dietary supplements.

Is DMAE like DMAA?

What's the difference between DMAE and DMAA? These are two different ingredients. DMAE, also known as dimethylaminoethanol is a precursor to the neurotransmitter acetylcholine and is an ingredient for helping support brain health and mood. There are no Beachbody products that currently use DMAA in its formulas.

Is DMAA a controlled substance?

Schedule 9 compounds are prohibited substances which have no therapeutic potential, for example Heroin (although there is the possibility of therapeutic use for this drug). The TGA has now made a ruling, announced today, and placed DMAA in appendix C of the scheduled drug list.

What is DMAA in pre workout?

DMAA (1,3-dimethylamylamine) is an amphetamine derivative that has been marketed in sports performance and weight loss products, many of which are sold as dietary supplements. DMAA, especially in combination with other stimulant ingredients such as caffeine, can be a health risk to consumers.

Is DMAA liver toxic?

"There have been two reported cases of liver failure associated with DMAA use in the military and recently 43 cases of hepatitis in Hawaii associated with OxyElitePro, a supplement containing DMAA, with two liver transplants and one death," the researchers noted in the woman's case report. 

How much DMAA is in OxyElite pro?

Background. OxyElite Pro (OEP) is a dietary supplement to increase metabolism which contains as key stimulant the ingredient 1,3-dimethylamylamine (DMAA).

Does DMAA increase dopamine?

DMAA appears to provide a sympathomimetic effect in human subjects. It mimics the effects on the sympathetic nervous system of neurotransmitters such as epinephrine, norepinephrine and dopamine. That said, few human studies have been conducted using DMAA or DMAA containing supplements.

Clinical Studies