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1, 3 DMAA

Overview

1,3-DMAA is a drug made synthetically in a laboratory. It was originally used as a nasal decongestant. Today, 1,3-DMAA is sold as a dietary supplement used for attention deficit-hyperactive disorder (ADHD), weight loss, improving athletic performance, and body building.

Some products claim that 1,3-DMAA naturally comes from rose geranium oil. Supplements that contain this ingredient sometimes list rose geranium, geranium oil, or geranium stems on the label. However, laboratory analysis shows that this drug probably does not come from this natural source. It is thought that these manufacturers have artificially added this drug to the supplement rather than obtaining it from a natural source. 1,3-DMAA is considered a drug in Canada and is not permitted in dietary supplements or natural health products.

Many athletes take 1,3-DMAA to improve performance. However, 1,3-DMAA was added to the World Anti-Doping Agency's prohibited substances list in 2010. Therefore, competitive athletes should avoid taking it.

Due to safety concerns, 1,3-DMAA has been removed from military stores in the US. It has also been banned in New Zealand. The US Food and Drug Administration (FDA) considers supplements containing 1,3-DMAA to be illegal. Its use has been linked to several reports of serious, life-threatening side effects.

Classification

Is a Form of:

Drug

Primary Functions:

Improve athletic performance

Also Known As:

DMAA, Forthan, Forthane, Floradrene, Fouramin, Geranamine

How Does It Work?

1,3-DMAA is thought to have stimulant effects similar to decongestants such as pseudoephedrine, ephedrine, and others. Some promoters say that it is a safer alternative to ephedrine. But there is no scientific information to back up this claim.

Uses

  • Obesity. Early research shows that taking 1,3-DMAA doesn't seem to help with weight loss.
  • Athletic performance.
  • Attention deficit-hyperactive disorder (ADHD).
  • Body building.
  • Memory and thinking skills (cognitive function).
  • Other conditions.

Recommended Dosing

The appropriate dose of 1,3-DMAA depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for 1,3-DMAA. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

1, 3 – DMAA Supplements Frequently Asked Questions

Why is DMAA banned?

Among the reasons DMAA is banned are: DMAA has no health benefits and is a toxic substance. Risks associated with its use include high blood pressure, psychiatric disorders, bleeding in the brain and stroke. Its long-term safety has not been demonstrated.

How long does 1/3 DMAA stay in your system?

The results from the Saudan laboratory found that 1,3-DMAA could be detected in urine samples up to 105 hours after administration of a 40 mg dose.

Will 1/3 Dimethylamylamine show on drug test?

Another drug that has been associated with false positive results for amphetamine is 1,3 dimethylamylamine (DMAA). DMAA has sympathomimetic activity and is an ingredient in some dietary and weight-loss supplements.

Will DMAA fail a drug test?

In the confirmation test by the GC-MS, DMAA does not cause a positive result for methamphetamine/amphetamine. However, DMAA did cause more specimens to be sent to the Confirmation Department for further testing and hence caused an increase in workload for the DoD laboratories (3).

Is DMAA a controlled substance?

Schedule 9 compounds are prohibited substances which have no therapeutic potential, for example Heroin (although there is the possibility of therapeutic use for this drug). The TGA has now made a ruling, announced today, and placed DMAA in appendix C of the scheduled drug list.

How much DMAA should I take?

The pills con- tained DMAA at an estimated dose of approximately 150 mg based on labeled dose information (lab analysis confirmed dosage of 132 mg), a dose approximately 3-5 times that normally suggested by most pre-workout dietary supplements.

Will DMAA show on a military drug test?

Service Members who ingest products containing DMAA may screen presumptively positive on the initial immunoassay tests for amphetamines. The DoD drug testing laboratories are now using at least two different amphetamine immunoassay reagent kits to screen urine specimens.

Is Dmha legal?

On April 10, 2019, the FDA issued 12 warning letters to companies whose dietary supplement products are in violation of the law. The FDA considers dietary supplements containing DMHA to be adulterated. DMHA is also known as: 1,5-Dimethylhexylamine.

Is DMAA a steroid?

DMAA is banned by the US Military because two soliders died after taking it during basic training. It's apparently serious stuff. It also has pregnenolone, a steroid hormone banned by the olympics so I figured that would give me some sort of insight into what taking an illegal steroid would be like.

What are the side effects of DMAA?

Unfortunately, when you get beyond 500 mg and over 1000 mg additional side effects such as palpitations, anxiety and dizziness can result. When stimulants such as DMAA are then added to the caffeine in such energy drinks, this could produce a more powerful effect.

Is DMAA illegal in the UK?

Once the product has entered the UK, it is not illegal to buy or possess it. "Our ruling means that products containing DMAA are, effectively, unlicensed medicines."

Is DMAA still banned?

It is banned by many sports authorities and governmental agencies. Despite multiple warning letters from the FDA, as of 2019, the stimulant remains available in sports and weight loss supplements.

What does DMAA do to the body?

DMAA works by stimulating the neurotransmitter norepinephrine (noradrenaline). This increases heart rate, breathing rate, causes vasoconstriction, and can give the user feelings of intense focus, increased energy, alertness, and strength.

How long does it take for DMAA to kick in?

The peak DMAA concentration for all subjects was observed within 3–5 hours following ingestion and was very similar across subjects, with a mean of ~70 ng∙mL-1. Heart rate, blood pressure, and body temperature were largely unaffected by DMAA treatment.

Does DMAA get you high?

DMAA or 1, 3-Dimethylamylamine is a very potent stimulant that has gained much popularity in sports performance drinks in recent years. ... Many companies marketing products containing DMAA claim that it is a “natural stimulant” derived from the seed, stem, or oil of the geranium plant.

Clinical Studies